Auxano® Technology

Discontinuous Surface Topology, Engineered for a Continuous Bony Interface

Auxano®: Revolutionizing Hard Tissue Integration for Orthopedic Implants

Auxano® is transforming the orthopedic industry by enhancing hard tissue integration and redefining the bone-implant interface across various implant types. As a leading platform technology, Auxano® brings orthopedic professionals closer to personalized implants tailored to individual anatomies. This innovation supports advancements in minimally invasive surgery (MIS), enabling faster, more efficient procedures with minimal hardware and simplified joint preparation.

At Auxano® Medical, we prioritize safety, effectiveness, and surgeon collaboration to deliver state-of-the-art orthopedic solutions. Our evolving designs offer continuous fixation interfaces, optimized stress transfer, comprehensive fixation options, and seamless compatibility with advanced fabrication technologies. Explore how Auxano® is setting new standards in orthopedic implant design and surgical innovation.

Continuous Fixation Interface

Efficient Stress Transfer

Primary & Secondary Fixation

Fully Engineered Solution

Technology Compatibility

Fabrication Compatibility

Continuous Fixation Interface

Negative features in porous implants require bone to grow along tortuous paths that are not interconnected, resulting in a discrete “discontinuous phase” of bone. Some porous surfaces have displayed incomplete bone migration to the base of the implant interface.

The positive pillar features of the Auxano® morphology take the role of the “discontinuous phase”, creating alleys for bone to interdigitate between. In this case, the growing bony interface forms an uninhibited “continuous phase” encapsulating the pillared structures.
Growing bone interdigitates within and around each pillar on the implant surface. Thus, the bone is the “continuous phase” enveloping the discrete pillared projections.
Efficient Stress Transfer

The order of magnitude difference in material properties between bone and metals used in orthopedic implants has plagued the industry for decades.

The Auxano® surface morphology provides a solution to this challenge by creating a structural transition zone where the stiffness of the pillar surface can be adjusted through manipulation of the pillar geometry and distribution. This allows the implant to gradually transition to the stiffness of the bone substrate.

The Auxano® technology allows greater control of the bone volume percent at the bone-implant interface by varying pillar spacing, size, length, and material characteristics.

Efficient Stress Transfer
Primary & Secondary Fixation
Primary & Secondary Fixation

Non-union, implant loosening, and implant infection are the top causes of failure in orthopedic devices. Primary and secondary fixation at the bone-implant interface is where these failed devices struggle to fulfill the desired outcome.

The Auxano® surface provides a high friction interface for initial implant stability. Once the interface is stable, bone migrates into the open matrix of pillars, eventually creating an interface that is more than 50% bone. Secondary fixation is achieved by maintaining a strain environment that sustains the long-term health and viability of the ingrown bone as shown in the histology image.
Initial motion control supplies the strain-limited environment necessary for new, primary bone formation. By maintaining intimate contact, the bone environment remains optimal and moves through its natural process of migration and wound healing. Studies to date show healthy osteon formation along the surface of the Auxano textured bulk implant with no indication of excessive inflammation or fibroplasia.
Fully Engineered Solution

Each location in the body brings about different local loading conditions and bone anatomy. There is a need to have control over the implant surface to account for the variability in these conditions.

The Auxano® morphology has a wide design space that is adaptable to the specific anatomical environment.
The ability to adjust array spacing, pillar geometry, and material characteristics are what give Auxano® the versatility to account for local loading conditions and bone anatomy.
Fully Engineered Solution
Technology Compatibility

Many surface technologies can only be applied on their own when an application may require a combination of surface morphologies to elicit the desired cellular response.

Since Auxano® is a macro surface morphology, it is compatible with micro and nano surface technologies and can combine the benefits provided by surfaces on multiple scales.
By existing on the 300-1000 µm scale, the Auxano® technology is able coexist with micro (1-300 µm) and nano (< 1 µm) scale surface technologies.
Fabrication Compatibility

A large percentage of the commonly used surface technologies are only compatible with certain substrate materials made using specific fabrication techniques.

The Auxano® surface morphology is made of the same substrate material as the implant, which opens it up to various additive and subtractive fabrication techniques. In an in-vivo study using an ovine model, multiple substrate materials were compared, and each demonstrated bone ingrowth viability using the Auxano® technology (https://doi.org/10.1016/j.jmbbm.2021.104775).
Being integral to the substrate material of the implant, there is the ability to fabricate the Auxano® morphology using the same fabrication technique as the overall implant. This also provides an innate shear strength to the surface and prevents any risk of delamination that is present when a coating or add-on process is applied to the surface.
Fabrication Compatibility

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