About
Our Origin
From deep space ion thruster to orthopedic implants? This is the story of Auxano. In the 1980’s, NASA was working on ion bombardment technology with unique surface features that had the potential for commercial use. NASA contacted Case Western Reserve University, where research was being done on different surface morphologies and tissue interfaces. At that time, Dr. George Picha was in graduate school at Case Western Reserve University studying biomaterials and gained a deeper understanding of surface morphologies arising from ion beam technology. Additionally, a number of in-vivo studies were conducted involving tissue interface mechanics. Using this knowledge, Dr. Picha was able to develop a patented pillared surface morphology for soft tissue clinical application.
Entry into Medical Space
Based on evidence from an independent study, industry became interested in the pillar technology and the affect it had on soft tissue wound healing. Eventually, an industry partner licensed the patent and, during clinical application, the pillars inhibited contracture of the soft tissue implant.
An Orthopedic Revival
After the initial industry adoption of the technology, Dr. Picha explored other interests for two decades. However, a breakthrough opportunity arose during a foundational research project on hard tissue, revealing an exceptional tissue response with Auxano® technology. This discovery reignited interest in its potential and paved the way for its first application in hard tissue. Collaborative studies with the University of Akron, Cleveland Clinic, and the University of New South Wales evaluated orthopedic materials—including titanium, PEEK, and high-density polyethylene (HDPE)—in models ranging from canine and sheep specimens to human cadavers. The outstanding mechanical performance, detailed histology, and advanced micro-CT imaging highlighted Auxano®’s transformative potential for hard tissue implants, opening new avenues for innovative medical device applications.
