Auxano® Research
Auxano® Medical’s history of scientific research and seven-plus decades of collective experience illustrate its ongoing commitment to the future of implant technology.
From NASA to New Frontiers in Orthopedic Implants
Auxano® Medical’s origin story begins in the 1980s with NASA. At the time, the space administration was working on ion thruster technology which can create unique surface features. The generated surface morphologies showed potential for medical applications.
NASA approached Case Western Reserve University in Cleveland, Ohio, for research assistance. Auxano® Medical’s founder Dr. George Picha was a graduate student there at the time, studying biomaterials. He participated in and learned from the research project, eventually putting that knowledge to use beyond grad school. Dr. Picha went on to develop Auxano® Medical’s patented pillared surface morphology for soft tissue clinical use.
Decades later, the Auxano® Medical team, with a combined 75+ years of experience, continues to invest in studying surface morphology. The result of its work brings the world closer to orthopedic implants that give patients the best possible outcomes.
Publications
Peer-reviewed publications detailing in vivo osseointegration testing validated the unique orthopedic potential of Auxano® Medical’s surface morphology.
In-Vivo response to a novel pillared surface morphology for osseointegration in an ovine model
Journal of the Mechanical Behavior of Biomedical Materials
Gregory C. Causey, George J. Picha, Jamey Price, Matthew H. Pelletier, Tian Wang, William R. Walsh
Summary: In-vivo testing using an ovine model examined the effects of pillar morphology on bone ingrowth and mechanical performance. Results showed pillared osseointegrative surface supports robust bone ingrowth exceeding 40 to 80% new bone occupied in cancellous and cortical bone, respectively, at 12 weeks. Testing of cortical samples also demonstrated robust resistance to pushout.
The effect of a novel pillar surface morphology and material composition demonstrates uniform osseointegration
Journal of the Mechanical Behavior of Biomedical Materials
Gregory C. Causey, George J. Picha, Jamey Price, Matthew H. Pelletier, Tian Wang, William R. Walsh
Summary: In-vivo testing using an ovine model examined the effects of pillar morphology on bone ingrowth and mechanical performance. Results showed pillared osseointegrative surface supports robust bone ingrowth exceeding 40 to 80% new bone occupied in cancellous and cortical bone, respectively, at 12 weeks. Testing of cortical samples also demonstrated robust resistance to pushout.
Presentations:
Several prestigious societies and conferences worldwide showcased Auxano® Medical research on surface morphology.
A Pillar Based, Macro-Scale, Osseointegrative Interface with Variable Biomechanics Based on Material Composition and Pillar Geometry.
33rd Congress of the International Society for Technology in Arthroplasty.
September 2022.
System for High-Precision Biomechanical Testing of Motions of Multiple Small Bones in Close Anatomic Proximity.
33rd Congress of the International Society for Technology in Arthroplasty.
September 2022.
Using Digital Image Correction to Track Joint Fusion Micromotion in 6 Degrees of Freedom.
33rd Congress of the International Society for Technology in Arthroplasty.
September 2022.
Biomechanically Tuning the Strength and Stiffness of an Open Pillar Implant Interface.
Combined UHMWPE, PEEK & Polymer Implant Additive Manufacturing Conference.
June 2022.
In-vivo Response to a Discrete, Marco-Scale Surface Morphology Enabling Continuous Bony In-Growth: Effects of Surface Variations and Implant Material Composition.
Spine Society of Australia.
April 2019.
Results of In-vivo Testing of a Novel Macro-Scale Osseointegration Surface Morphology.
PEEK Symposium.
April 2019.
Bone-Implant Stiffness and Load Sharing During Bone Ingrowth into a Novel Surface Topology.
Orthopaedic Research Society.
February 2019.
An Introduction to Controlled Surface Morphologies and the Hard Tissue Response.
State of Spine Surgery Summit & Think Tank.
June 2018.
An Introduction to Controlled Surface Morphologies and the Hard Tissue Response.
International Society for the Advancement of Spine Surgery.
April 2018.
Posters:
Several prestigious societies and conferences worldwide showcased Auxano® Medical research on surface morphology.
Automated Finite Element Modeling Approach for Investigating a Range of Implant Surface Topologies.
Orthopaedic Research Society. February 2023.
Osseointegration into Ultra-high Molecular Weight Polyethylene Utilizing an Open, Macro-Scale Surface Morphology.
Orthopaedic Research Society. February 2022.
Accurate Segmentation and Normalization of μCT Data from In-Vivo Testing of a Macro-Scale Pillar Morphology.
Orthopaedic Research Society. February 2022.
Method and Hardware for Minimally Invasive, High-Precision Motion Tracking of Small Bones.
Orthopaedic Research Society. February 2022.
Benefits and Pitfalls of Tracking Joint Fusion Micromotion in 6DOF using Digital Image Correlation.
Orthopaedic Research Society.
February 2022.
Effects of Materials on Osseointegration into a Novel Macro Scale Surface Morphology.
Orthopaedic Research Society. February 2019.
Osseointegration of Novel Macro-Structured Implant Surface.
Orthopaedic Research Society.
March 2017.
Learn More About the Future of Orthopedics
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