About

Our Origin

From deep space ion thruster to orthopedic implants? This is the story of Auxano®. In the 1980’s, NASA was working on ion bombardment technology with unique surface features that had the potential for commercial use. NASA contacted Case Western Reserve University, where research was being done on different surface morphologies and tissue interfaces. At that time, Dr. George Picha was in graduate school at Case Western Reserve University studying biomaterials and gained a deeper understanding of surface morphologies arising from ion beam technology. Additionally, a number of in-vivo studies were conducted involving tissue interface mechanics. Using this knowledge, Dr. Picha was able to develop a patented pillared surface morphology for soft tissue clinical application.

Entry into Medical Space

Based on evidence from an independent study, industry became interested in the pillar technology and the affect it had on soft tissue wound healing. Eventually, an industry partner licensed the patent and, during clinical application, the pillars inhibited contracture of the soft tissue implant.

An Orthopedic Revival

In the 20 years that followed the first industry involvement with the technology, Dr. Picha shifted his focus to other interests. In time, an opportunity to revisit the use of Auxano® occurred as part of a basic research project in hard tissue giving rise to a very unique tissue response. This gave new life to the technology and led to its first application in hard tissue. A series of studies, involving the University of Akron, Cleveland Clinic, and University of New South Wales, assessed orthopedic materials, such as titanium, PEEK, and high-density polyethylene (HDPE), being implanted into dogs, cadaver specimens, and sheep. The promising mechanical performance, histology, and micro CT images brought about a new opportunity for device application in hard tissue implants with the Auxano® pillared technology.

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